Skip to main content
Chemistry LibreTexts

Chem 4320/5320: Biochemistry 1

  • Page ID
    165250
  • Thumbnail: An enzyme binding site that would normally bind substrate can alternatively bind a competitive inhibitor, preventing substrate access. Dihydrofolate reductase is inhibited by methotrexate which prevents binding of its substrate, folic acid. Binding site in blue, inhibitor in green, and substrate in black (PDB: 4QI9​). (CC BY 4.0; Thomas Shafee).

    • Was this article helpful?