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Chemistry LibreTexts

Acid Anhydrides react with water to form carboxylic acids

  • Page ID
    5903
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    Acid Anhydrides react with water to form carboxylic acids

    General Reaction

    File:/C:\Users\Gantor\AppData\Local\Temp\msohtmlclip1\01\clip_image002.png

    Example 1:
    2.jpg

    Mechanism

    1) Nucleophilic Attack by the Alcohol

    File:/C:\Users\Gantor\AppData\Local\Temp\msohtmlclip1\01\clip_image006.png

    2) Deprotonation by pyridine

    File:/C:\Users\Gantor\AppData\Local\Temp\msohtmlclip1\01\clip_image008.png

    3) Leaving group removal

    File:/C:\Users\Gantor\AppData\Local\Temp\msohtmlclip1\01\clip_image010.png

    4) Protonation of the carboxylate

    File:/C:\Users\Gantor\AppData\Local\Temp\msohtmlclip1\01\clip_image012.png

    Contributors


    Acid Anhydrides react with water to form carboxylic acids is shared under a CC BY-NC-SA 4.0 license and was authored, remixed, and/or curated by LibreTexts.

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