Acid Anhydrides React with Amines to Form Amides
- Page ID
- 5902
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Acid Anhydrides react with amines to form amides
General Reaction
| Example 1: |
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Mechanism
1) Nucleophilic Attack by the Amine
2) Deprotonation by the amine
3) Leaving group removal
Contributors
Prof. Steven Farmer (Sonoma State University)