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Acid Anhydrides React with Amines to Form Amides

  • Page ID
    5902
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    Acid Anhydrides react with amines to form amides

    General Reaction

    1.jpg

    Example 1:
    2.jpg

    Mechanism

    1) Nucleophilic Attack by the Amine

    3.jpg

    2) Deprotonation by the amine

    4.jpg

    3) Leaving group removal

    5.jpg

    Contributors

    Prof. Steven Farmer (Sonoma State University)


    Acid Anhydrides React with Amines to Form Amides is shared under a not declared license and was authored, remixed, and/or curated by LibreTexts.

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