Acid Anhydrides react with alcohols to form esters
- Page ID
- 5904
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Acid Anhydrides react with alcohols to form esters
General Reaction
Reactions of anhydrides use Pyridine as a solvent
| Example 1: |
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Mechanism
1) Nucleophilic Attack by the Alcohol
2) Deprotonation by pyridine
3) Leaving group removal
4) Protonation of the carboxylate
Contributors
Prof. Steven Farmer (Sonoma State University)