Acid Anhydrides react with alcohols to form esters
- Page ID
- 5904
Acid Anhydrides react with alcohols to form esters
General Reaction
Reactions of anhydrides use Pyridine as a solvent
Example 1: |
---|
![]() |
Mechanism
1) Nucleophilic Attack by the Alcohol
2) Deprotonation by pyridine
3) Leaving group removal
4) Protonation of the carboxylate
Contributors
Prof. Steven Farmer (Sonoma State University)