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4: Carbon-Heteroatom Bond-Forming Reactions

Last updated

Mar 16, 2021
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- 3.3: Problems and Reference
- 4.1: Allylic Substitution Reactions

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Asymmetric carbon-heteroatom bond formation is among the fundamentally important reactions. This module covers the carbon-heteroatom bond-forming reactions using transition-metal-complex as well as the chiral Lewis acid catalyzed protocols.

4.1: Allylic Substitution Reactions
4.2: Aza-Claisen Rearrangement and Related Reactions
Aza-Claisen rearrangement, known as the Overman rearrangement, has been extensively studied that allows us to synthesize chiral allylic amines from achiral allylic imidates with excellent enantioselectivity.
4.3: Hydroamination of Alkenes
4.4: Hydroalkoxylation of Allenes
4.5: Oxidation Reactions
4.6: Aziridination of Alkenes
4.7: Amination of Carbonyl Compounds
4.8: Boration of Alkenes
Organoboranes are useful reagents for organic synthesis. Recently, catalytic methods have been developed for enantioselective boration of unsaturated substrates.
4.9: Hydrophosphonylation of Imines
4.10: Problems and Reference

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