4.3: Hydroamination of Alkenes
Scandium 3,3'-tris(phenylsilyl)binaphtholate can be used as a highly active catalyst for the synthesis of pyrrolidine via intramolecular hydroamination (Scheme \(\PageIndex{1}\)).
Chiral neutral zirconium amidate has been used for hydroamination of primary aminoalkenes with 93% ee (Scheme \(\PageIndex{1}\)).