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4.3: Hydroamination of Alkenes

  • Page ID
    168789
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    Scandium 3,3'-tris(phenylsilyl)binaphtholate can be used as a highly active catalyst for the synthesis of pyrrolidine via intramolecular hydroamination (Scheme \(\PageIndex{1}\)).

    clipboard_e39abbf7fccd61a849e0c9de71358d359.png
    Scheme \(\PageIndex{1}\)

    Chiral neutral zirconium amidate has been used for hydroamination of primary aminoalkenes with 93% ee (Scheme \(\PageIndex{1}\)).

    clipboard_e1b62924da1a39ef5d02431d06aa982a0.png
    Scheme \(\PageIndex{2}\)

    This page titled 4.3: Hydroamination of Alkenes is shared under a CC BY-SA license and was authored, remixed, and/or curated by Tharmalingam Punniyamurthy (National Programme on Technology Enhanced Learning (NPTEL) ) .