This chapter highlights synthetically useful sigmatropic rearrangements including hydride shifts, the Cope rearrangement, the Claisen rearrangement, and the Wittig rearrangement.
One characteristic shared by most pericyclic reactions, and noted in many cases described above, is their stereospecificity. This is not the first class of reactions for which a characteristic stereos...One characteristic shared by most pericyclic reactions, and noted in many cases described above, is their stereospecificity. This is not the first class of reactions for which a characteristic stereospecificity has been noted. Substitution reactions may proceed randomly or by "inversion" or "retention" of configuration. Elimination reactions may occur in an "anti" or "syn" fashion, or may be configurationally random. The terms "syn" and "anti" have also been applied to 1,2-addition reactions.
