Chem1102: Drug Discovery - From the Laboratory to the Clinic
- Page ID
- 255562
Medicinal chemistry is a field at the intersection of chemistry, biology, physiology, business, and ethics. This is a course for first-year, non-science major undergraduate students exploring the process of rational drug design, from discovery to use by patients. This is a course for first-year, non-science major undergraduate students, based on the course outline described by Wenzel et al., J. Chem. Educ. 2020, 97, 414-420 doi:10.1021/acs.jchemed.9b00691
- Front Matter
- 1: Atomic Structure
- 2: Ionic Bonding and Simple Ionic Compounds
- 3: Covalent Bonding and Simple Molecular Compounds
- 4: Noncovalent bonds
- 5: Organic Molecules
- 6: Lipids
- 7: Conformations and Stereochemistry
- 8: Acids and Bases
- 9: Amino Acids, Proteins, and Enzymes
- 10: Equilibrium and Kinetics- Making Drugs Stick
- 11: Molecular Genetics
- 12: Chemical and Biological Databases
- 13: Computer-Aided Drug Design
- 14: Does it work? Clinical Testing
- 15: What is it worth? Estimating Value
- 16: Appendix
- Back Matter
Thumbnail: A pharmacophore model of the benzodiazepine binding site on the GABAA receptor. White sticks = carbon atoms of diazepam, green = carbon atoms of CGS-9896, red = oxygen, blue = nitrogen. The H1 and H2/A3 are presumed hydrogen bond. (Public Domain, Boghog2 via Wikidepia)