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Chemistry LibreTexts

Synthesis of Nitriles

  • Page ID
    5361
  • Nitriles are formed by an SN2 reaction between a bromide and sodium cyanide

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    1o Amides can be converted to nitriles by dehydration with thionyl chloride

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    Addition of cyanide (-:C≡N) to an aldehyde or ketone forms a cyanohydrin

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