5: Hydrophobicity
- Page ID
- 294287
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- 5.1: Hydrophobic Solvation - Thermodynamics
- The hydrophobic effect refers to the free energy penalty that one pays to solvate a weakly interacting solute.
- 5.2: Hydrophobic Solvation- Solute Size Effect
- To create a new interface there are enthalpic and entropic penalties. The influence of each of these factors depends on the size of the solute (R) relative to the scale of hydrogen bonding structure in the liquid (correlation length, ℓ , ~0.5–1.0 nm).