20: Carboxylic Acid Derivatives and Nitriles
- Page ID
- 183120
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learning objectives
After reading this chapter and completing ALL the exercises, a student can be able to
- describe the structure and physical properties of carboxylic acid derivatives and nitriles (section 22.1)
- determine the structure of carboxylic acid derivatives and nitriles from their elemental analysis and spectral data (MS, IR 1H NMR & 13C NMR) (section 22.2)
- predict the products and specify the reagents to interconvert between a carboxylic acid and its derivatives (section 22.3)
- predict the products and specify the reagents to hydrolyze carboxylic acid derivatives (22.4)
- predict the products and specify the reagents for transesterification reactions (section 22.5)
- predict the products and specify the reagents for reduction reactions of carboxylic acid derivatives (section 22.6)
- predict the products and specify the reagents for organometallic reactions with carboxylic acid derivatives (section 22.7)
- predict the products and specify the reagents for the synthesis and reactions of
- acyl chlorides (section 22.4)
- anhydrides (section 22.5)
- esters (section 22.6)
- amides (section 22.7)
- nitriles (section 22.8)
- thioesters (section 22.9)
- step-growth (condensation) polymers via ester and amide bonds (section 22.10)
- discuss the chemistry of beta-lactams and biological acylation (section 22.11 and 22.12 respectively)
- combine the reactions studied to date to develop efficient and effective multiple-step synthesis
Please note: IUPAC nomenclature and important common names of carboxylic acid derivatives and nitriles were explained in Chapter 3.