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8.7: A Look Ahead - Addition of Carbon and Hydride Nucleophiles to Carbonyls

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    242276
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    We have seen in this chapter a number of reactions in which oxygen and nitrogen nucleophiles add to carbonyl groups. Other nucleophiles are possible in carbonyl addition mechanisms: in chapters 12 and 13, for example, we will examine in detail some enzyme-catalyzed reactions where the attacking nucleophile is a resonance stabilized carbanion (usually an enolate ion):

    clipboard_ed3b3ed4e917e4f72755b1d75e9a98645.png

    Then in chapter 15, we will see how the carbonyl groups on aldehydes and ketones can be converted to alcohols through the nucleophilic addition of what is essentially a hydride (\(H^-\)) ion.

    clipboard_e334f4df2f24579f465f9007f09560a89.png

    fig 29


    This page titled 8.7: A Look Ahead - Addition of Carbon and Hydride Nucleophiles to Carbonyls is shared under a CC BY-NC-SA 4.0 license and was authored, remixed, and/or curated by Tim Soderberg.

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