Substitution Reactions Last updated Jan 23, 2023 Save as PDF F. The Dehydration of Butan-2-ol Carboxyl Substitution Page ID1152 ( \newcommand{\kernel}{\mathrm{null}\,}\) Topic hierarchyKinetics of Nucleophilic Substitution ReactionsSN1Effects of Solvent, Leaving Group, and Nucleophile on Unimolecular SubstitutionSN1 ReactionGetting StartedKnowledge BaseKnown Issues