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  • https://chem.libretexts.org/Courses/SUNY_Oneonta/Chem_322_Lecture_Content/01%3A_Phosphate_Transfer_Reactions/1.08%3A_Phosphate_Diesters_in_DNA_and_RNA
    Phosphate diesters play an absolutely critical role in nature - they are the molecular 'tape' that connect the individual nucleotides in DNA and RNA via a sugar-phosphate backbone.
  • https://chem.libretexts.org/Courses/SUNY_Oneonta/Organic_Chemistry_with_a_Biological_Emphasis_(SUNY_Oneonta)/09%3A_Phosphate_Transfer_Reactions/9.07%3A_Hydrolysis_of_Organic_Phosphates
    While kinase enzymes catalyze the phosphorylation of organic compounds, enzymes called phosphatases catalyze dephosphorylation reactions.
  • https://chem.libretexts.org/Courses/Oregon_Institute_of_Technology/OIT%3A_CHE_333_-_Organic_Chemistry_III_(Lund)/New_Page/9%3A_Phosphate_Transfer_Reactions/9.6%3A_Hydrolysis_of_Organic_Phosphates
    While kinase enzymes catalyze the phosphorylation of organic compounds, enzymes called phosphatases catalyze dephosphorylation reactions.
  • https://chem.libretexts.org/Courses/Oregon_Institute_of_Technology/OIT%3A_CHE_332_--_Organic_Chemistry_II_(Lund)/9%3A_Phosphate_Transfer_Reactions/9.2%3A_Phosphate_Transfer_Reactions_-_An_Overview
    In a phosphate transfer reaction, a phosphate group is transferred from a phosphate group donor molecule to a phosphate group acceptor molecule. A very important aspect of biological phosphate transfe...In a phosphate transfer reaction, a phosphate group is transferred from a phosphate group donor molecule to a phosphate group acceptor molecule. A very important aspect of biological phosphate transfer reactions is that the electrophilicity of the phosphorus atom is usually enhanced by the Lewis acid (electron-accepting) effect of one or more magnesium ions.
  • https://chem.libretexts.org/Bookshelves/Organic_Chemistry/Book%3A_Organic_Chemistry_with_a_Biological_Emphasis_v2.0_(Soderberg)/09%3A_Phosphate_Transfer_Reactions/9.0E%3A_9.E%3A_Phosphate_Transfer_Reactions_(Exercise)
    It turns out that the same enzyme is also capable of catalyzing the transfer of the phosphate group from glucose-6-phosphate to the hydroxyl group on carbon #6 of another glucose molecule (instead of ...It turns out that the same enzyme is also capable of catalyzing the transfer of the phosphate group from glucose-6-phosphate to the hydroxyl group on carbon #6 of another glucose molecule (instead of to water, which is the natural reaction).
  • https://chem.libretexts.org/Courses/SUNY_Oneonta/Chem_322_Lecture_Content/01%3A_Phosphate_Transfer_Reactions/1.02%3A_Overview_of_Phosphate_Groups
    Phosphate is everywhere in biochemistry. As we were reminded in the introduction to this chapter, our DNA is linked by phosphate. The function of many proteins is regulated - switched on and off - by ...Phosphate is everywhere in biochemistry. As we were reminded in the introduction to this chapter, our DNA is linked by phosphate. The function of many proteins is regulated - switched on and off - by enzymes which attach or remove a phosphate group from the side chains of serine, threonine, or tyrosine residues.
  • https://chem.libretexts.org/Courses/Oregon_Institute_of_Technology/OIT%3A_CHE_333_-_Organic_Chemistry_III_(Lund)/New_Page/9%3A_Phosphate_Transfer_Reactions/9.7%3A_Phosphate_Diesters_in_DNA_and_RNA
    Phosphate diesters play an absolutely critical role in nature - they are the molecular 'tape' that connect the individual nucleotides in DNA and RNA via a sugar-phosphate backbone.
  • https://chem.libretexts.org/Courses/Oregon_Institute_of_Technology/OIT%3A_CHE_333_-_Organic_Chemistry_III_(Lund)/New_Page/9%3A_Phosphate_Transfer_Reactions/9.3%3A_ATP_The_Principal_Phosphate_Group_Donor
    Thus far we have been very general in our discussion of phosphate transfer reactions, referring only to generic 'donor' and 'acceptor' species. It's time to get more specific. The most important donor...Thus far we have been very general in our discussion of phosphate transfer reactions, referring only to generic 'donor' and 'acceptor' species. It's time to get more specific. The most important donor of phosphate groups in the cell is a molecule called adenosine triphosphate, commonly known by its abbreviation ATP.
  • https://chem.libretexts.org/Courses/Oregon_Institute_of_Technology/OIT_(Lund)%3A_Organic_Chemistry_with_a_Biological_Emphasis_(Soderberg)/09%3A_Phosphate_Transfer_Reactions/9.S%3A_Phosphate_Transfer_Reactions_(Summary)
    Your learning goal for this chapter is to recognize and understand what is happening in these phosphate group transfer reactions, and to gain a basic understanding of the chemistry of phosphate and ot...Your learning goal for this chapter is to recognize and understand what is happening in these phosphate group transfer reactions, and to gain a basic understanding of the chemistry of phosphate and other phosphate groups. You should be able to identify the apical and equatorial positions in the pentavalent transition state of a phosphate transfer reaction, and recognize that the reaction results in inversion at the phosphorus center.
  • https://chem.libretexts.org/Courses/Oregon_Institute_of_Technology/OIT%3A_CHE_332_--_Organic_Chemistry_II_(Lund)/9%3A_Phosphate_Transfer_Reactions/9.1%3A_Overview_of_Phosphate_Groups
    Phosphate is everywhere in biochemistry. As we were reminded in the introduction to this chapter, our DNA is linked by phosphate. The function of many proteins is regulated - switched on and off - by ...Phosphate is everywhere in biochemistry. As we were reminded in the introduction to this chapter, our DNA is linked by phosphate. The function of many proteins is regulated - switched on and off - by enzymes which attach or remove a phosphate group from the side chains of serine, threonine, or tyrosine residues.
  • https://chem.libretexts.org/Bookshelves/Organic_Chemistry/Book%3A_Organic_Chemistry_with_a_Biological_Emphasis_v2.0_(Soderberg)/09%3A_Phosphate_Transfer_Reactions/9.02%3A_Overview_of_Phosphate_Groups
    Phosphate is everywhere in biochemistry. As we were reminded in the introduction to this chapter, our DNA is linked by phosphate. The function of many proteins is regulated - switched on and off - by ...Phosphate is everywhere in biochemistry. As we were reminded in the introduction to this chapter, our DNA is linked by phosphate. The function of many proteins is regulated - switched on and off - by enzymes which attach or remove a phosphate group from the side chains of serine, threonine, or tyrosine residues.

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