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- https://chem.libretexts.org/Courses/Oregon_Institute_of_Technology/OIT_(Lund)%3A_Organic_Chemistry_with_a_Biological_Emphasis_(Soderberg)/07%3A_Acid-base_Reactions/7.03%3A_Structural_Effects_on_Acidity_and_BasicityNow that we know how to quantify the strength of an acid or base, our next job is to gain an understanding of the fundamental reasons behind why one compound is more acidic or more basic than another....Now that we know how to quantify the strength of an acid or base, our next job is to gain an understanding of the fundamental reasons behind why one compound is more acidic or more basic than another. This is a big step: we are, for the first time, taking our knowledge of organic structure and applying it to a question of organic reactivity.
- https://chem.libretexts.org/Courses/Oregon_Institute_of_Technology/OIT_(Lund)%3A_Organic_Chemistry_with_a_Biological_Emphasis_(Soderberg)/07%3A_Acid-base_Reactions/7.06%3A_Carbon_AcidsSo far, we have limited our discussion of acidity and basicity to heteroatom acids, where the acidic proton is bound to an oxygen, nitrogen, sulfur, or halogen. However, carbon acids - in which the pr...So far, we have limited our discussion of acidity and basicity to heteroatom acids, where the acidic proton is bound to an oxygen, nitrogen, sulfur, or halogen. However, carbon acids - in which the proton to be donated is bonded to a carbon atom - play an integral role in biochemistry.
- https://chem.libretexts.org/Courses/Oregon_Institute_of_Technology/OIT%3A_CHE_333_-_Organic_Chemistry_III_(Lund)/New_Page/12%3A_Reactions_at_the_-Carbon_Part_I/12.1%3A_Review_of_Acidity_at_the_-CarbonLet's review what we learned in section 7.6 about the acidity of a proton on an a-carbon and the structure of the relevant conjugate base, the enolate ion. Remember that this acidity can be explained ...Let's review what we learned in section 7.6 about the acidity of a proton on an a-carbon and the structure of the relevant conjugate base, the enolate ion. Remember that this acidity can be explained by the fact that the negative charge on the enolate conjugate base is delocalized by resonance to both the α -carbon and the carbonyl oxygen.
- https://chem.libretexts.org/Courses/Westminster_College/CHE_180_-_Inorganic_Chemistry/7%3A_Chapter_7_-_Acid-Base_Theories/7.2%3A_Acidity_of_the_Hexaaqua_IonsThis page explains why hexaaqua complex ions are acidic.
- https://chem.libretexts.org/Courses/Lakehead_University/Analytical_I/8%3A_Titrimetric_Methods/8.2%3A_Acid%E2%80%93Base_TitrationsAcid–base titrations, in which an acidic or basic titrant reacts with a titrand that is a base or an acid, is probably the most common titration used by students in laboratories. To understand the rel...Acid–base titrations, in which an acidic or basic titrant reacts with a titrand that is a base or an acid, is probably the most common titration used by students in laboratories. To understand the relationship between an acid–base titration’s end point and its equivalence point we must know how the pH changes during a titration. We will learn how to calculate a titration curve using the equilibrium calculations from Chapter 6.
- https://chem.libretexts.org/Bookshelves/Inorganic_Chemistry/Supplemental_Modules_and_Websites_(Inorganic_Chemistry)/Coordination_Chemistry/Complex_Ion_Chemistry/Acidity_of_the_Hexaaqua_IonsThis page explains why hexaaqua complex ions are acidic.
- https://chem.libretexts.org/Courses/Oregon_Institute_of_Technology/OIT%3A_CHE_333_-_Organic_Chemistry_III_(Lund)/New_Page/7%3A_Acid-base_Reactions/7.8%3A_Effects_of_enzyme_microenvironment_on_acidity_and_basicityVirtually all biochemical reactions take place inside the active site pocket of an enzyme, rather than free in aqueous solution. The microenvironment inside an enzyme's active site can often be very d...Virtually all biochemical reactions take place inside the active site pocket of an enzyme, rather than free in aqueous solution. The microenvironment inside an enzyme's active site can often be very different from the environment outside in the aqueous solvent. Consider, for example, the side chain carboxylate on an aspartate residue in an enzyme.
- https://chem.libretexts.org/Bookshelves/Inorganic_Chemistry/Inorganic_Chemistry_(LibreTexts)/08%3A_Chemistry_of_the_Main_Group_Elements/8.13%3A_The_Halogens/8.13.02%3A_Chemical_Properties_of_the_Halogens/8.13.2.07%3A_The_Acidity_of_the_Hydrogen_HalidesThis page discusses the acidity of the hydrogen halides: hydrogen fluoride, hydrogen chloride, hydrogen bromide and hydrogen iodide. It begins by describing their physical properties and synthesis and...This page discusses the acidity of the hydrogen halides: hydrogen fluoride, hydrogen chloride, hydrogen bromide and hydrogen iodide. It begins by describing their physical properties and synthesis and then explains what happens when they react with water to make acids such as hydrofluoric acid and hydrochloric acid.
- https://chem.libretexts.org/Courses/SUNY_Oneonta/Chem_322_Lecture_Content/07%3A_Reactions_at_the_-Carbon_Part_I/7.02%3A_Review_of_Acidity_at_the_-CarbonLet's review what we learned in section 7.6 about the acidity of a proton on an a-carbon and the structure of the relevant conjugate base, the enolate ion. Remember that this acidity can be explained ...Let's review what we learned in section 7.6 about the acidity of a proton on an a-carbon and the structure of the relevant conjugate base, the enolate ion. Remember that this acidity can be explained by the fact that the negative charge on the enolate conjugate base is delocalized by resonance to both the α -carbon and the carbonyl oxygen.
- https://chem.libretexts.org/Bookshelves/Organic_Chemistry/Book%3A_Organic_Chemistry_with_a_Biological_Emphasis_v2.0_(Soderberg)/12%3A_Reactions_at_the_-Carbon_Part_I/12.02%3A_Review_of_Acidity_at_the_-CarbonLet's review what we learned in section 7.6 about the acidity of a proton on an a-carbon and the structure of the relevant conjugate base, the enolate ion. Remember that this acidity can be explained ...Let's review what we learned in section 7.6 about the acidity of a proton on an a-carbon and the structure of the relevant conjugate base, the enolate ion. Remember that this acidity can be explained by the fact that the negative charge on the enolate conjugate base is delocalized by resonance to both the α -carbon and the carbonyl oxygen.
- https://chem.libretexts.org/Courses/Northern_Michigan_University/CH_215%3A_Chemistry_of_the_Elements_Fall_2023/06%3A_Transition_Metals_and_Coordination_Chemistry/6.17%3A_Complex_Ion_Chemistry/6.17.01%3A_Acidity_of_the_Hexaaqua_IonsThis page explains why hexaaqua complex ions are acidic.
