7.7: Coenzyme A

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Apr 2, 2021
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- 7.6: ATP as Energy carrier
- 7.8: The Chemistry of NAD+ and FAD

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Coenzyme A

Coenzyme A (CoA) is a central compound in metabolism. It is a derivative of Pantothenic acid (vitamin B5) and a component of coenzyme A (CoA).The main functions of CoA is the activation and transfer of acyl groups. This function involves the reactive sulfhydryl group through the formation of thioester linkages with acyl groups.

Structure of coenzyme A: 1: 3′-phosphoadenosine. 2: diphosphate, organophosphate anhydride. 3: pantoic acid. 4: β-alanine. 5: cysteamine. Image by NEUROtiker, Public domain, via Wikimedia Commons.

Structure of acetyl-CoA

Image by Bryan Derksen (original) and DMacks (talk) (color-change), Public domain, via Wikimedia Commons.

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Dr. Michael Blaber

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Coenzyme A

Structure of acetyl-CoA

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