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Conversion of a Carboxylic Acid to an Amide

  • Page ID
    5533
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    The direct reaction of a carboxylic acid with an amine would be expected to be difficult because the basic amine would deprotonate the carboxylic acid to form a highly unreactive carboxylate. However when the ammonium carboxylate salt is heated to a temperature above 100 oC water is driven off and an amide is formed.

    General Reaction

    1.jpg

    Going from reactants to products simply

    2.jpg

    Contributors

    Prof. Steven Farmer (Sonoma State University)


    Conversion of a Carboxylic Acid to an Amide is shared under a not declared license and was authored, remixed, and/or curated by LibreTexts.

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