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21.2: Synthetic Outcomes

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    The attack of hydride ions as nucleophiles on electrophilic carbon creates a new C–H bond, therefore the carbon atom undergoes a reduction (gain of bonds to hydrogen). Because of this, this type of reactions is commonly referred to as reductions, even though the mechanism is a nucleophilic addition. Likewise, the hydride delivering agent is more commonly referred to as a hydride reducing agent, or just reducing agent.

    Unlike the attack of carbon nucleophiles on a carbonyl carbon, the attack of a hydride ion produces no new C–C bonds and therefore there is no expansion of the carbon chain. Consequently, only primary and secondary alcohols can be made by this approach.



    This page titled 21.2: Synthetic Outcomes is shared under a not declared license and was authored, remixed, and/or curated by Sergio Cortes.

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