- use R groups to draw generic functional groups - refer to section 3.1
Drawing Generic (abbreviated) Organic Structures
In chapter 2, we learned to recognize and distinguish between organic functional groups. Often when drawing organic structures, chemists find it convenient to use the letter 'R' to designate part of a molecule outside of the region of interest. "R" represents the "Rest of the Molecule". If we just want to refer in general to a functional group without drawing a specific molecule, for example, we can use 'R groups' to focus attention on the group of interest:
The 'R' group is a convenient way to abbreviate the structures of large biological molecules, especially when we are interested in something that is occurring specifically at one location on the molecule. For example, in chapter 15 when we look at biochemical oxidation-reduction reactions involving the flavin molecule, we will abbreviate a large part of the flavin structure which does not change at all in the reactions of interest:
As an alternative, we can use a 'break' symbol to indicate that we are looking at a small piece or section of a larger molecule. This is used commonly in the context of drawing groups on large polymers such as proteins or DNA.
Finally, 'R' groups can be used to concisely illustrate a series of related compounds, such as the family of penicillin-based antibiotics.
Using abbreviations appropriately is a very important skill to develop when studying organic chemistry in a biological context, because although many biomolecules are very large and complex (and take forever to draw!), usually we are focusing on just one small part of the molecule where a change is taking place.