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5: Structure Reactivity Relationships

Last updated

Aug 10, 2022
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- 4.4.2: Reactive Intermediates
- 5.1: Correlations of Structure with Reactivity of Aromatic Compounds

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5.1: Correlations of Structure with Reactivity of Aromatic Compounds
This section is concerned with the quantitative correlation of reaction rates and equilibria of organic reactions with the structure of the reactants. We will restrict the discussion to benzene derivatives. The focus is on a remarkably simple treatment developed by L. P. Hammett in 1935, which has been tremendously influential. Hammett's correlation covers chemical reactivity, spectroscopy and other physical properties, and even the biological activity of drugs.
5.2: Linear Free Energy Relationships

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