Skip to main content
Chemistry LibreTexts

5.6: Rotary Evaporation

  • Page ID
    95713
  • \( \newcommand{\vecs}[1]{\overset { \scriptstyle \rightharpoonup} {\mathbf{#1}} } \) \( \newcommand{\vecd}[1]{\overset{-\!-\!\rightharpoonup}{\vphantom{a}\smash {#1}}} \)\(\newcommand{\id}{\mathrm{id}}\) \( \newcommand{\Span}{\mathrm{span}}\) \( \newcommand{\kernel}{\mathrm{null}\,}\) \( \newcommand{\range}{\mathrm{range}\,}\) \( \newcommand{\RealPart}{\mathrm{Re}}\) \( \newcommand{\ImaginaryPart}{\mathrm{Im}}\) \( \newcommand{\Argument}{\mathrm{Arg}}\) \( \newcommand{\norm}[1]{\| #1 \|}\) \( \newcommand{\inner}[2]{\langle #1, #2 \rangle}\) \( \newcommand{\Span}{\mathrm{span}}\) \(\newcommand{\id}{\mathrm{id}}\) \( \newcommand{\Span}{\mathrm{span}}\) \( \newcommand{\kernel}{\mathrm{null}\,}\) \( \newcommand{\range}{\mathrm{range}\,}\) \( \newcommand{\RealPart}{\mathrm{Re}}\) \( \newcommand{\ImaginaryPart}{\mathrm{Im}}\) \( \newcommand{\Argument}{\mathrm{Arg}}\) \( \newcommand{\norm}[1]{\| #1 \|}\) \( \newcommand{\inner}[2]{\langle #1, #2 \rangle}\) \( \newcommand{\Span}{\mathrm{span}}\)\(\newcommand{\AA}{\unicode[.8,0]{x212B}}\)

    The preferred method for solvent removal in the laboratory is by use of a rotary evaporator (also known as a "rotovap"). A rotary evaporator is essentially a reduced pressure distillation: a solution in a round bottomed flask is placed in the water bath of the apparatus, and rotated while the system is partially evacuated (by a water aspirator or vacuum pump). The reduced pressure in the apparatus causes the solvent to boil at a lower temperature than normal, and rotating the flask increases the liquid's surface area and thus the rate of evaporation.

    • 5.6A: Overview of Rotary Evaporation
      It is very common for a desired compound to be dissolved in a solvent during regular manipulations in the laboratory. The preferred method for solvent removal in the laboratory is by use of a rotary evaporator, also known as a "rotovap". A rotary evaporator is essentially a reduced pressure distillation: a solution in a round bottomed flask is placed in the water bath of the apparatus , and rotated while the system is partially evacuated (by a water aspirator or vacuum pump).
    • 5.6B: Step-by-Step Procedures for Rotary Evaporation
    • 5.6C: Troubleshooting Rotary Evaporation
      If the solvent fails to boil on the rotary evaporator even after one minute, consider whether a mistake may have been made. For example, it may be that you are trying to evaporate the aqueous layer from a separatory funnel step instead of the organic layer. Alternatively, the water bath may need to be heated to a higher temperature depending on the boiling point of the solvent.

    Contributors and Attributions

    • Lisa Nichols (Butte Community College). Organic Chemistry Laboratory Techniques is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. Complete text is available online.


    This page titled 5.6: Rotary Evaporation is shared under a CC BY-NC-ND 4.0 license and was authored, remixed, and/or curated by Lisa Nichols via source content that was edited to the style and standards of the LibreTexts platform; a detailed edit history is available upon request.