Most of the reactions of the 1,4-dicarbonyl compounds are the conventional reactions expected for isolated carbonyl groups. An important exception is formation of azacylclopentadiene (pyrrole) derivatives from 1,4-dicarbonyl compounds and ammonia or primary amines:
These reactions are reasonably general and also can be used to prepare compounds with oxygen and sulfur in five-membered rings.
Contributors and Attributions
John D. Robert and Marjorie C. Caserio (1977) Basic Principles of Organic Chemistry, second edition. W. A. Benjamin, Inc. , Menlo Park, CA. ISBN 0-8053-8329-8. This content is copyrighted under the following conditions, "You are granted permission for individual, educational, research and non-commercial reproduction, distribution, display and performance of this work in any format."