Part IX. Closing Thoughts
- Page ID
- 241125
\( \newcommand{\vecs}[1]{\overset { \scriptstyle \rightharpoonup} {\mathbf{#1}} } \)
\( \newcommand{\vecd}[1]{\overset{-\!-\!\rightharpoonup}{\vphantom{a}\smash {#1}}} \)
\( \newcommand{\id}{\mathrm{id}}\) \( \newcommand{\Span}{\mathrm{span}}\)
( \newcommand{\kernel}{\mathrm{null}\,}\) \( \newcommand{\range}{\mathrm{range}\,}\)
\( \newcommand{\RealPart}{\mathrm{Re}}\) \( \newcommand{\ImaginaryPart}{\mathrm{Im}}\)
\( \newcommand{\Argument}{\mathrm{Arg}}\) \( \newcommand{\norm}[1]{\| #1 \|}\)
\( \newcommand{\inner}[2]{\langle #1, #2 \rangle}\)
\( \newcommand{\Span}{\mathrm{span}}\)
\( \newcommand{\id}{\mathrm{id}}\)
\( \newcommand{\Span}{\mathrm{span}}\)
\( \newcommand{\kernel}{\mathrm{null}\,}\)
\( \newcommand{\range}{\mathrm{range}\,}\)
\( \newcommand{\RealPart}{\mathrm{Re}}\)
\( \newcommand{\ImaginaryPart}{\mathrm{Im}}\)
\( \newcommand{\Argument}{\mathrm{Arg}}\)
\( \newcommand{\norm}[1]{\| #1 \|}\)
\( \newcommand{\inner}[2]{\langle #1, #2 \rangle}\)
\( \newcommand{\Span}{\mathrm{span}}\) \( \newcommand{\AA}{\unicode[.8,0]{x212B}}\)
\( \newcommand{\vectorA}[1]{\vec{#1}} % arrow\)
\( \newcommand{\vectorAt}[1]{\vec{\text{#1}}} % arrow\)
\( \newcommand{\vectorB}[1]{\overset { \scriptstyle \rightharpoonup} {\mathbf{#1}} } \)
\( \newcommand{\vectorC}[1]{\textbf{#1}} \)
\( \newcommand{\vectorD}[1]{\overrightarrow{#1}} \)
\( \newcommand{\vectorDt}[1]{\overrightarrow{\text{#1}}} \)
\( \newcommand{\vectE}[1]{\overset{-\!-\!\rightharpoonup}{\vphantom{a}\smash{\mathbf {#1}}}} \)
\( \newcommand{\vecs}[1]{\overset { \scriptstyle \rightharpoonup} {\mathbf{#1}} } \)
\( \newcommand{\vecd}[1]{\overset{-\!-\!\rightharpoonup}{\vphantom{a}\smash {#1}}} \)
For instructors interested in building into their laboratory curriculum a method development exercise based on the use of response surfaces, the following experiments from the Journal of Chemical Education may be of interest:
“Introduction to the Design and Optimization of Experiments Using Response Surface Methodology. A Gas Chromatography Experiment for the Instrumentation Laboratory,” Lang, P. L.; Miller, B. I.; Nowak, A. T. J. Chem. Educ., 2006, 83, 280–282.
“Experimental Design and Optimization: Application to a Grignard Reaction,” Bouzidi, N.; Gozzi, C. J. Chem. Educ., 2008, 85, 1544–1547.
“Visualizing the Solute Vaporization Interference in Flame Atomic Absorption Spectroscopy,” Dockery, C. R.; Blew, M. J.; Goode, S. R. J. Chem. Educ., 2008, 85, 854–858.
“Attaining Optimal Conditions: An Advanced Undergraduate Experiment that Introduces Experimental Design and Optimization,” Van Ryswyk, H.; Van Hecke, G. R. J. Chem. Educ., 1991, 68, 878–882.
“Optimization of HPLC and GC Separations Using Response Surfaces: Three Experiments for the Instrumental Analysis Laboratory,” Harvey, D. T.; Byerly, S.; Bowman, A.; Tomlin, J. J. Chem. Educ., 1991, 68, 162–168.
“Central Composite Experimental Designs: Applied to Chemical Systems,” Palasota, J. A.; Deming, S. N. J. Chem. Educ., 1992, 69, 560–563.
“Mixture Design Experiments Applied to the Formulation of Colorant Solutions,” Gozálvez, J. M.; García-Díaz, J. C. J. Chem. Educ., 2006, 83, 647–650.
“Experimental Design, Near-Infrared Spectroscopy, and Multivariate Calibration: An Advanced Project in Chemometrics,” J. Chem. Educ., 2012, 89, 1566–1571.