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Thermodynamic Control

  • Page ID
    43039
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    When two or more reversible reactions of the same reactants compete under a given set of conditions, the system is said to be under thermodynamic control, and the major product is the more stable product, which is called the thermodynamic product. The conditions that ensure that the system is under thermodynamic control is called thermodynamic conditions.

    thermodynamiccontrol1.png

    K1, K2 = equilibrium constants

    thermodynamiccontrol2.png

    If C is more stable than D, given that the two reactions have the same reactants,

    K1 > K2,
    [C] > [D]

    C = major product, D = minor product

    eg: Reaction of 1,3-butadiene (1) with HCl at high temperature

    thermodynamiccontrol3.png

    Two products were isolated:

    thermodynamiccontrol4.png

    2 is more stable than 3 because it has the more highly substituted, therefore, stronger double bond. Experimentally, 2 is the major product, implying that the system is under thermodynamic control, i.e., the reactions leading to products 2 and 3 are reversible. The conditions used to ensure reversibility of the reactions, namely, high temperature, are thermodynamic conditions.

    thermodynamiccontrol5.png

    see also kinetic control


    This page titled Thermodynamic Control is shared under a All Rights Reserved (used with permission) license and was authored, remixed, and/or curated by Gamini Gunawardena via source content that was edited to the style and standards of the LibreTexts platform.

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