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Robinson Annulation

Last updated

Feb 28, 2022
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- Robinson Annelation
- R,S Convention

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Robinson annulation or Robinson annelation is a synthetic protocol used to construct cyclohexane rings. Mechanistically, Robinson annulation is Michael addition followed by intramolecular aldol condensation.

eg:

mechanism:

1. Michael addition

2. Intramolecular aldol condensation

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