Skip to main content
Chemistry LibreTexts

Robinson Annulation

  • Page ID
    42561
  • Robinson annulation or Robinson annelation is a synthetic protocol used to construct cyclohexane rings.  Mechanistically, Robinson annulation is Michael addition followed by intramolecular aldol condensation.

    eg:

    mechanism:

    1.  Michael addition

     

    2. Intramolecular aldol condensation