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Michael Addition

  • Page ID
    40674
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    1,4-Addition reactions of α, β–unsaturated carbonyl compounds and α, β–unsaturated nitriles with resonance-stabilized carbon nucleophiles, such as enolate ions and enamines, are known as Michael addition. The α, β–unsaturated compounds undergoing Michael addition is called the Michael acceptor, the nucleophile Michael donor, and the product Michael adduct.

    eg:

    michaeladdition1.png

    mechanism:

    michaeladdition2.png

    see also Robinson annulation


    This page titled Michael Addition is shared under a All Rights Reserved (used with permission) license and was authored, remixed, and/or curated by Gamini Gunawardena via source content that was edited to the style and standards of the LibreTexts platform; a detailed edit history is available upon request.

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