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Prochiral Molecule

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  • A prochiral molecule is an achiral molecule containing at least one pair of enantiotopic ligands.




    1 is achiral, and Ha and Hb in 1 are enantiotopic.  Thus, 1 is prochiral.  In a prochiral molecule, an atom bearing a pair of enantiotopic ligands is called a prochiral center or prochirality center.  If a prochirality center is a carbon atom, it can also be called a prochiral carbon.



    see also chiral molecule, chiral center