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Post-Translational Modification

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  • The chemical modification of an amino acid residue in a peptide molecule is called post-translational modification, the consequence of which is the occurrence of nonstandard amino acids in peptides.

    eg: The protein collagen contains 5-hydroxylysine, a nonstandard amino acid, which is formed by the modification of lysine, a standard amino acid, after the collagen molecule is synthesized.

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