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Chemistry LibreTexts

Nucleophilic Aromatic Substitution

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A nucleophilic aromatic substitution is a nucleophilic substitution reaction in which it is a leaving group on an aromatic ring that is replaced by the nucleophile.

eg. 1:

nucleophilicaromaticsubstitution1.png

net reaction:

nucleophilicaromaticsubstitution2.png

eg. 2:

nucleophilicaromaticsubstitution3.png

net reaction:

nucleophilicaromaticsubstitution4.png

see also benzyne mechanism, SNAr mechanism, nucleophilic aliphatic substitution


This page titled Nucleophilic Aromatic Substitution is shared under a All Rights Reserved (used with permission) license and was authored, remixed, and/or curated by Gamini Gunawardena via source content that was edited to the style and standards of the LibreTexts platform.

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