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Chemistry LibreTexts

Nucleophilic Acyl Substitution

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A nucleophilic acyl substitution reaction is a nucleophilic substitution reaction in which the net reaction is the replacement of a ligand bonded to the carbonyl carbon in an acyl group with a nucleophile.

eg. 1:

nulceophilicacylsubstitution1.png

net reaction:

nulceophilicacylsubstitution2.png

eg. 2:

nulceophilicacylsubstitution3.png

net reaction:

nulceophilicacylsubstitution4.png


This page titled Nucleophilic Acyl Substitution is shared under a All Rights Reserved (used with permission) license and was authored, remixed, and/or curated by Gamini Gunawardena via source content that was edited to the style and standards of the LibreTexts platform.

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