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Chemistry LibreTexts

Mannich Base

[ "article:topic", "Mannich Base", "authorname:ggunawardena" ]
  • Page ID
    40651
  • The acid-catalyzed reaction of an enolizable aldehyde or an enolizable ketone with an imminium ion, usually generated in situ by the reaction of formaldehyde with a secondary amine, followed by a base to give a β-aminoaldehyde of a β-aminoketone, respectively, is known as the Mannich reaction. The product of the Mannich reaction is called the Mannich base.

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