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Friedel-Crafts Acylation

Last updated

Feb 28, 2022
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- Friedel-Crafts Alkylation

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Friedel-Crafts acylation is the reaction of benzene and substituted benzenes with acid chlorides in the presence of a Lewis acid catalyst. The net reaction is an electrophilic aromatic substitution.

eg:

net reaction:

mechanism:

Step 1:

Step 2:

see also acylium ion, Friedel-Crafts alkylation, Fries rearrangement

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