Skip to main content
Chemistry LibreTexts

Epimers

[ "article:topic", "authorname:ggunawardena" ]
  • Page ID
    40170
  • Epimers are diastereomers that contain more than one chiral center but differ from each other in the absolute configuration at only one chiral center.

    eg:

     

     

    1 and 2 have the same molecular formula and the same structural formula and, therefore, stereoisomers.  1 and 2 are not mirror images of each other and, therefore, are diastereomers.

     

     

    Diastereomers 1 and 2 differ from each other in the absolute configuration at only one chiral center.  Thus, 1 and 2 are epimers.

    In epimers the chiral carbon atoms whose absolute configuration makes the two compounds different are called the epimeric carbons.