1.38: Central Nervous System
- Page ID
- 125350
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Use the following key to answer Questions 1-16.
- 1,2, and 3 are correct
- 1 and 3 are correct
- 2 and 4 are correct
- only 4 is correct
- all are correct
- The Central nervous system is comprised of:
- brain
- sympathetic nerves
- spinal chord
- parasympathetic nerves
- The cerebrospinal fluid:
- is about 150 mL
- is produced and reabsorbed at a rate of about 150 mL/day
- is replaced every 4 to 6 hours
- is constant in volume
- The blood brain barrier:
- is a physiological barrier separating brain and CSF fluid from substances carried in the blood
- allows brain and CSF composition to be different
- is determined at cell surfaces of the choroid plexus
- is permeable to water
- The blood brain barrier is impermeable to:
- proteins
- carbon monoxide
- aniline dyes
- alcohol
- In the case of drugs, the ability to cross the blood brain barrier:
- is greater if it is lipid soluble
- is less if it is ionized
- is dependent upon disease status
- is dependent upon amino acid transport
- In normal CSF:
- protein levels are less than 800 mg/L
- protein levels are equal to serum
- glucose levels are 60-80% of serum
- glucose levels are equal to serum
- The brain’s energy reserve:
- is similar to that of the liver
- is primarily the lipid of adipose tissue
- is in the grey matter
- is very small
- The primary energy source(s) of the brain is/are:
- fatty acids
- triglycerides
- cholesterol
- glucose
- Factors that determine whether a molecule will be excluded from the brain by the blood-brain barrier include:
- molecular weight
- molecular polarity
- molecular ionization
- capillary permeability
- In the norepinephrine neuron the precursor amino acid tyrosine is taken up and converted to:
- levodopa
- dopamine
- phenylalanine
- norepinephrine
- Serotonin neurons within the control nervous system use which amino acid precursor(s) to form the neurotransmitter?
- tyrosine
- phenylalanine
- norepinephrine
- tryptophan
- Which of the following drugs is (are) used to treat psychiatric disorders:
- tricyclic antidepressants
- lithium
- monoamine oxidase inhibitors
- phenytoin
- When monitoring drugs such as amitriptyline and imipramine
- the type of illness should be considered
- dexamethasone depression test results should be consulted
- care must be taken to keep specimens refrigerated
- the metabolites should also be monitored
- Which of the following can act as neurotransmitters?
- acetylcholine
- gamma-amino-butyric acid
- dopamine
- norepinephrine
- Lithium is most useful for the treatment of:
- unipolar depression
- classical schizophrenia
- psychosis
- bipolar depression
- The dexamethasone suppression test of cortisol is used to confirm the diagnosis of:
- unipolar depression
- bipolar depression
- psychoses
- classic schizophrenia
- none of the above
- Antipsychotic drugs vary very little in their potency and greatly in their metabolism
- True
- False
- Answer
-
- b (p. 789)
- e (p. 789)
- e (p. 790)
- b (p. 790-791)
- a (p. 790)
- b (p. 791, 801-803)
- d (p. 792)
- d (p. 792)
- e (p. 790)
- c (p. 793)
- d (p. 793)
- a (p. 800)
- d (p. 803-804)
- e (p. 792-793)
- d (p. 800, 807)
- a (p. 801)
- b (p. 798-799)