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- https://chem.libretexts.org/Bookshelves/Physical_and_Theoretical_Chemistry_Textbook_Maps/Physical_Chemistry_(LibreTexts)/25%3A_Solutions_II_-_Nonvolatile_Solutes/25.04%3A_Osmotic_Pressure_can_Determine_Molecular_MassesThis page discusses the selective permeability of membrane materials influencing osmosis, crucial for biological processes. It highlights the calculation and application of osmotic pressure in water p...This page discusses the selective permeability of membrane materials influencing osmosis, crucial for biological processes. It highlights the calculation and application of osmotic pressure in water purification, and methods like osmometry and chromatography for determining molar masses, especially of polymers. Furthermore, the page describes melting point depression as a technique for assessing purity in organic synthesis, particularly for pharmaceuticals.
- https://chem.libretexts.org/Bookshelves/Analytical_Chemistry/Analytical_Chemistry_2.1_(Harvey)/15%3A_Quality_Assurance/15.01%3A_The_Analytical_Perspective_RevisitedThe page discusses the analytical approach in chemistry, highlighting the problem-solving process and the importance of feedback loops in improving analytical methods. It emphasizes the role of qualit...The page discusses the analytical approach in chemistry, highlighting the problem-solving process and the importance of feedback loops in improving analytical methods. It emphasizes the role of quality assurance programs in controlling systematic and random errors, ensuring results are unbiased and within defined confidence intervals.
- https://chem.libretexts.org/Bookshelves/Analytical_Chemistry/Analytical_Chemistry_2.1_(Harvey)/14%3A_Developing_a_Standard_Method/14.02%3A_Verifying_the_MethodThe page outlines the process of determining a method's effectiveness in a single-analyst scenario, involving the evaluation of precision, accuracy, and detection limits through single-operator charac...The page outlines the process of determining a method's effectiveness in a single-analyst scenario, involving the evaluation of precision, accuracy, and detection limits through single-operator characteristics, blind analysis, and ruggedness testing. It highlights the comparison of new and standard methods and describes ruggedness testing through experimental design to assess variability factors.
- https://chem.libretexts.org/Bookshelves/Analytical_Chemistry/Analytical_Chemistry_2.1_(Harvey)/15%3A_Quality_Assurance/15.06%3A_Additional_ResourcesThis page lists various resources related to quality assurance and quality control in chemical research and analysis. The resources include journal articles discussing the integration of QA/QC into qu...This page lists various resources related to quality assurance and quality control in chemical research and analysis. The resources include journal articles discussing the integration of QA/QC into quantitative analysis, environmental analytical chemistry, undergraduate research, quantitative analysis, and bioanalytical experiments.
- https://chem.libretexts.org/Bookshelves/Analytical_Chemistry/Analytical_Chemistry_2.1_(Harvey)/15%3A_Quality_Assurance/15.04%3A_Evaluating_Quality_Assurance_DataThe text discusses two approaches to developing a quality assurance program in analytical chemistry: the prescriptive approach and the performance-based approach. The prescriptive approach involves a ...The text discusses two approaches to developing a quality assurance program in analytical chemistry: the prescriptive approach and the performance-based approach. The prescriptive approach involves a strict protocol for quality assessment, often required by regulatory agencies, while the performance-based approach allows laboratories flexibility, using control charts to monitor statistical control. Control charts help detect errors, ensuring precision and accuracy in analysis.
- https://chem.libretexts.org/Courses/Los_Angeles_Trade_Technical_College/Analytical_Chemistry/2%3A_Analytical_Chemistry_2.0_(Harvey)/16%3A_Quality_Assurance/16.1%3A_The_Analytical_Perspective%E2%80%94RevisitedThe focus of this chapter is on the two principal components of a quality assurance program: quality control and quality assessment. In addition, considerable attention is given to the use of control ...The focus of this chapter is on the two principal components of a quality assurance program: quality control and quality assessment. In addition, considerable attention is given to the use of control charts for routinely monitoring the quality of analytical data.
- https://chem.libretexts.org/Courses/Los_Angeles_Trade_Technical_College/Analytical_Chemistry/2%3A_Analytical_Chemistry_2.0_(Harvey)/16%3A_Quality_Assurance/16.2%3A_Quality_ControlQuality control encompasses all activities that bring an analysis into statistical control. The most important facet of quality control is a set of written directives describing the relevant laborator...Quality control encompasses all activities that bring an analysis into statistical control. The most important facet of quality control is a set of written directives describing the relevant laboratory-specific, technique-specific, sample-specific, method-specific, and protocol-specific operations. Good laboratory practices (GLPs) describe the general laboratory operations that we must follow in any analysis.
- https://chem.libretexts.org/Bookshelves/Analytical_Chemistry/Analytical_Chemistry_2.1_(Harvey)/03%3A__The_Vocabulary_of_Analytical_Chemistry/3.06%3A_ProtocolsA protocol is a set of stringent written guidelines crucial for agency approval of analytical results. It includes procedures for internal and external QA/QC to ensure accuracy. The EPA's protocol for...A protocol is a set of stringent written guidelines crucial for agency approval of analytical results. It includes procedures for internal and external QA/QC to ensure accuracy. The EPA's protocol for trace metal analysis using atomic absorption spectroscopy involves calibration with a method blank and three standards. Calibration is verified through ICV and ICB samples, needing results within ??10% accuracy.
- https://chem.libretexts.org/Bookshelves/Analytical_Chemistry/Analytical_Chemistry_2.1_(Harvey)/15%3A_Quality_Assurance/15.03%3A_Quality_AssessmentThe text explains that quality control directives are crucial for analysis but not enough to ensure statistical control, which is managed by quality assessment???a key part of quality assurance. Quali...The text explains that quality control directives are crucial for analysis but not enough to ensure statistical control, which is managed by quality assessment???a key part of quality assurance. Quality assessment helps maintain, detect, and suggest solutions for loss of statistical control. It includes internal methods, like analyzing duplicate samples and spikes, and external methods, such as laboratory certification by an agency.
- https://chem.libretexts.org/Courses/Lakehead_University/Analytical_I/3%3A_The_Vocabulary_of_Analytical_Chemistry/3.6%3A_ProtocolsA protocol is a set of stringent written guidelines specifying an exact procedure that must be followed before an agency will accept the results of an analysis. A protocol contains explicit instructio...A protocol is a set of stringent written guidelines specifying an exact procedure that must be followed before an agency will accept the results of an analysis. A protocol contains explicit instructions regarding internal and external quality assurance and quality control (QA/QC) procedures. The goal of internal QA/QC is to ensure that a laboratory’s work is both accurate and precise. External QA/QC is a process in which an external agency certifies a laboratory.
- https://chem.libretexts.org/Bookshelves/Analytical_Chemistry/Analytical_Chemistry_2.1_(Harvey)/15%3A_Quality_Assurance/15.02%3A_Quality_ControlQuality control in laboratories involves activities that ensure analyses are in statistical control, primarily through written directives that guide various operations. Good laboratory practices (GLPs...Quality control in laboratories involves activities that ensure analyses are in statistical control, primarily through written directives that guide various operations. Good laboratory practices (GLPs) outline general operations such as data recording, reagent preparation, and equipment maintenance. Good measurement practices (GMPs) focus on equipment use and calibration specific to techniques. Standard operations procedures (SOPs) provide detailed instructions for analyzing specific analytes.