In order to understand the nature of the leaving group, it is important to first discuss factors that help determine whether a species will be a strong base or weak base. If you remember from general ...In order to understand the nature of the leaving group, it is important to first discuss factors that help determine whether a species will be a strong base or weak base. If you remember from general chemistry, a Lewis base is defined as a species that donates a pair of electrons to form a covalent bond. The factors that will determine whether a species wants to share its electrons or not include electronegativity, size, and resonance.