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Chemistry LibreTexts

Active Methyne Compound

An active methyne compound is a compound that has the following general structural formula.

 

 

E1, E2 = a functional group that withdraws electrons by resonance

R= alkyl, aryl

 

eg:

 

activemethynecompound2.png

 

The conjugate base of an active methyne compound is highly resonance stabilized.

eg:

 

activemethynecompound3.png

 

Consequently, active methyne compounds, like active methylene compounds, are highly acidic and can be deprotonated, for all practical purposes, irreversibly, using common strong bases, such as the hydroxide ion or alkoxide ions.