4.7: Free Radicals and Health
- Page ID
- 440233
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\(\newcommand{\avec}{\mathbf a}\) \(\newcommand{\bvec}{\mathbf b}\) \(\newcommand{\cvec}{\mathbf c}\) \(\newcommand{\dvec}{\mathbf d}\) \(\newcommand{\dtil}{\widetilde{\mathbf d}}\) \(\newcommand{\evec}{\mathbf e}\) \(\newcommand{\fvec}{\mathbf f}\) \(\newcommand{\nvec}{\mathbf n}\) \(\newcommand{\pvec}{\mathbf p}\) \(\newcommand{\qvec}{\mathbf q}\) \(\newcommand{\svec}{\mathbf s}\) \(\newcommand{\tvec}{\mathbf t}\) \(\newcommand{\uvec}{\mathbf u}\) \(\newcommand{\vvec}{\mathbf v}\) \(\newcommand{\wvec}{\mathbf w}\) \(\newcommand{\xvec}{\mathbf x}\) \(\newcommand{\yvec}{\mathbf y}\) \(\newcommand{\zvec}{\mathbf z}\) \(\newcommand{\rvec}{\mathbf r}\) \(\newcommand{\mvec}{\mathbf m}\) \(\newcommand{\zerovec}{\mathbf 0}\) \(\newcommand{\onevec}{\mathbf 1}\) \(\newcommand{\real}{\mathbb R}\) \(\newcommand{\twovec}[2]{\left[\begin{array}{r}#1 \\ #2 \end{array}\right]}\) \(\newcommand{\ctwovec}[2]{\left[\begin{array}{c}#1 \\ #2 \end{array}\right]}\) \(\newcommand{\threevec}[3]{\left[\begin{array}{r}#1 \\ #2 \\ #3 \end{array}\right]}\) \(\newcommand{\cthreevec}[3]{\left[\begin{array}{c}#1 \\ #2 \\ #3 \end{array}\right]}\) \(\newcommand{\fourvec}[4]{\left[\begin{array}{r}#1 \\ #2 \\ #3 \\ #4 \end{array}\right]}\) \(\newcommand{\cfourvec}[4]{\left[\begin{array}{c}#1 \\ #2 \\ #3 \\ #4 \end{array}\right]}\) \(\newcommand{\fivevec}[5]{\left[\begin{array}{r}#1 \\ #2 \\ #3 \\ #4 \\ #5 \\ \end{array}\right]}\) \(\newcommand{\cfivevec}[5]{\left[\begin{array}{c}#1 \\ #2 \\ #3 \\ #4 \\ #5 \\ \end{array}\right]}\) \(\newcommand{\mattwo}[4]{\left[\begin{array}{rr}#1 \amp #2 \\ #3 \amp #4 \\ \end{array}\right]}\) \(\newcommand{\laspan}[1]{\text{Span}\{#1\}}\) \(\newcommand{\bcal}{\cal B}\) \(\newcommand{\ccal}{\cal C}\) \(\newcommand{\scal}{\cal S}\) \(\newcommand{\wcal}{\cal W}\) \(\newcommand{\ecal}{\cal E}\) \(\newcommand{\coords}[2]{\left\{#1\right\}_{#2}}\) \(\newcommand{\gray}[1]{\color{gray}{#1}}\) \(\newcommand{\lgray}[1]{\color{lightgray}{#1}}\) \(\newcommand{\rank}{\operatorname{rank}}\) \(\newcommand{\row}{\text{Row}}\) \(\newcommand{\col}{\text{Col}}\) \(\renewcommand{\row}{\text{Row}}\) \(\newcommand{\nul}{\text{Nul}}\) \(\newcommand{\var}{\text{Var}}\) \(\newcommand{\corr}{\text{corr}}\) \(\newcommand{\len}[1]{\left|#1\right|}\) \(\newcommand{\bbar}{\overline{\bvec}}\) \(\newcommand{\bhat}{\widehat{\bvec}}\) \(\newcommand{\bperp}{\bvec^\perp}\) \(\newcommand{\xhat}{\widehat{\xvec}}\) \(\newcommand{\vhat}{\widehat{\vvec}}\) \(\newcommand{\uhat}{\widehat{\uvec}}\) \(\newcommand{\what}{\widehat{\wvec}}\) \(\newcommand{\Sighat}{\widehat{\Sigma}}\) \(\newcommand{\lt}{<}\) \(\newcommand{\gt}{>}\) \(\newcommand{\amp}{&}\) \(\definecolor{fillinmathshade}{gray}{0.9}\)- Realize how free radicals can affect your health.
- Name some health conditions and diseases that can result from excessive free radical exposure.
- Provide examples of foods and beverages that contain antioxidants.
- Recognize chemicals in skin care products that can slow the effects of aging
Free radicals can be generated from a variety of processes. For example, combustion of any material will produce OH. (not hydroxide), NO. free radicals. Once inhaled, OH can enter the body and affect cells. Watch the video below to see how free radicals affect biological systems.
Free Radicals and Disease
Free radical exposure has been linked to cancer and a number of autoimmune diseases. One way of fighting free radicals is to consume or apply antioxidants. By providing sources of electrons, antioxidants can detour free radicals from attacking healthy cells in the body. The word wall below displays a variety of foods that are rich in antioxidants. Foods and beverages that are rich in vitamins A, C, and E provide sources of electrons for free radicals. Minerals like selenium are also antioxidants. For a more comprehensive list of foods are labeled as being antioxidants, click here.
Free Radicals and Aging
Some studies have linked biological free radical production to aging. In a cell's mitochondria, reactive oxygen species are naturally made. These substances damage fats, proteins, and mitochondria DNA. During this process, more free radicals are produced in the cell. Two of these destructive free radicals are superoxide (\(\ce{O2-^{}}\)) and nitrogen monoxide (\(\ce{NO}\)). These radicals have been linked to cancer, skin aging, heart disease, stroke, and other chronic diseases.
By eating more fruits and vegetables, many nutritionists believe the free radical effect can be reduced in regards to chronic disease. As for aging, many scientists believe that not just one theory can explain why aging occurs. For care of skin, dermatologists recommend that you reduce UV exposure. Ionizing radiation is a source of free radicals that can be minimized. Once the skin has been exposed to UV radiation, there is very little that can be done to counteract its effects.
Dermatologists and nutritionists recommend a diet rich in antioxidants (vitamins C, E, selenium, and coenzyme Q) to protect skin from damaging free radicals. Lotions, moisturizers, and sunscreens can contain these ingredients as well.
Watch the following video to understand how to care for your skin
- What are the purposes of the Epidermis and dermis in your skin?
- What do GAGS do:
- How can UVB help the body?
- What do the letters ROS represent?
- How do free radicals affect DNA, proteins, Fats, and the Dermis?
- What types of chemicals help repair damaged skin?
- When should the chemicals in question #6 not be used?
- How does Salicylic acid make skin appear more youthful?
- What is the purpose of applying hyaluronic (it is a humectant) acid to skin?
- Why are peptide products useless?
- According to this video, what is the best anti-aging product you can purchase?
Figure \(\PageIndex{11}\) Retinol
Manufacturers of anti-aging lotions or creams might use the scientific chemical names for the antioxidant ingredients. When purchasing these products, remember to translate them accordingly. Consumers often spend excessive amounts of money on anti-aging creams and lotions. The best way to reduce advanced aging is to protect your skin from ultraviolet exposure. In addition, selecting a skin-care product that contains a combination of some of the antioxidants below is helpful. Lastly, there is no need to pay a large amount of money for an anti-aging product.
| Antioxidant | Effect on skin |
|---|---|
| Vitamin E ( also known as Alpha-lipoic acid, 3-5%) | protects skin from sun damage |
| Vitamin A (also known as Retinoic acid, 0.01-0.1%) | treats fine wrinkles, age spots, and rough skin |
| Flavonoids (extracts from green tea or chocolate) | reverses sun damage |
| Vitamin B6 | treats fine wrinkles and protects skin from sun damage |
| Lycopene (a carotene that is present in tomatoes, watermelon, asparagus, and grapefruit) | protects skin from sun damage |
References
Contributors and Attributions
Isabella Quiros (Furman University)