Skip to main content
Chemistry LibreTexts

Titrimetry: Analysis of Literature Article

  • Page ID
  • \( \newcommand{\vecs}[1]{\overset { \scriptstyle \rightharpoonup} {\mathbf{#1}} } \) \( \newcommand{\vecd}[1]{\overset{-\!-\!\rightharpoonup}{\vphantom{a}\smash {#1}}} \)\(\newcommand{\id}{\mathrm{id}}\) \( \newcommand{\Span}{\mathrm{span}}\) \( \newcommand{\kernel}{\mathrm{null}\,}\) \( \newcommand{\range}{\mathrm{range}\,}\) \( \newcommand{\RealPart}{\mathrm{Re}}\) \( \newcommand{\ImaginaryPart}{\mathrm{Im}}\) \( \newcommand{\Argument}{\mathrm{Arg}}\) \( \newcommand{\norm}[1]{\| #1 \|}\) \( \newcommand{\inner}[2]{\langle #1, #2 \rangle}\) \( \newcommand{\Span}{\mathrm{span}}\) \(\newcommand{\id}{\mathrm{id}}\) \( \newcommand{\Span}{\mathrm{span}}\) \( \newcommand{\kernel}{\mathrm{null}\,}\) \( \newcommand{\range}{\mathrm{range}\,}\) \( \newcommand{\RealPart}{\mathrm{Re}}\) \( \newcommand{\ImaginaryPart}{\mathrm{Im}}\) \( \newcommand{\Argument}{\mathrm{Arg}}\) \( \newcommand{\norm}[1]{\| #1 \|}\) \( \newcommand{\inner}[2]{\langle #1, #2 \rangle}\) \( \newcommand{\Span}{\mathrm{span}}\)\(\newcommand{\AA}{\unicode[.8,0]{x212B}}\)

    Assigned Reading:

    Karita, S. and Kaneta, T. “Acid-base titrations using microfluidic paper-based analytical devices.” Analytical Chemistry 2014, 86, 12108–12114.

    Homework Questions:

    1. What is a primary standard and how are they commonly used in titrations?
    2. What primary standard is most often used for the standardization of aqueous bases (e.g., NaOH)? What primary standard is most often used for the standardization of aqueous acids (e.g., HCl)?
    3. What is a microfluidic device?
    4. Phenolphthalein is commonly used as an indicator for acid-base titrations. What color is it in solution at each pH listed below?
      1. <0                    b. 0–8.2                    c. 8.2–12                    d. >13

    In-class Questions:

    Please read the assigned article and discuss the following with your group members.

    1. How does the µPAD described overcome the typical disadvantages of acid-base titrations?


    1. How did the authors have to modify the device to detect acids instead of bases?


    1. Why did the authors choose phenolphthalein as the indicator for this device? Under what circumstances will this indicator not work?


    1. One disadvantage of the µPAD is limited precision in terms of the number of significant figures one can report in the concentration. For a traditional titration, what is the limiting factor for the precision of the measurement? For this new µPAD, what is the limiting factor?


    1. Propose a means by which you could increase the precision of the measurement.


    1. What dictates the range of concentrations that can be detected by the µPAD?


    Contributors and Attributions

    This page titled Titrimetry: Analysis of Literature Article is shared under a CC BY-NC-SA 4.0 license and was authored, remixed, and/or curated by Contributor.