Functional groups are common in organic chemistry and similar functional groups will have similar physical and/or reactive properties. Many of these functional groups can be made via substitution reac...Functional groups are common in organic chemistry and similar functional groups will have similar physical and/or reactive properties. Many of these functional groups can be made via substitution reactions, or are the starting materials for substitution reactions. Alcohols = R-OH (suffix –ol) Alkyl halides – R-X Amines – R-NH 2 (primary), R 2 NH (secondary), R 3 N (tertiary), R 4 N + (ammonium) Ethers – R-O-R’ Thiols (mercaptans) – R-SH Sulfides – R-S-R’