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  • https://chem.libretexts.org/Workbench/Chemistry_LHS_Bridge/18%3A_Proteins/18.04%3A_Case_Studies-_Proteins/18.4.02%3A_Enkephalines
    Apparently these peptides act as natural analgesics (pain-killers) and their action mimics that of morphine and other opiates. At present it is thought that the morphine-like effects are due to aromat...Apparently these peptides act as natural analgesics (pain-killers) and their action mimics that of morphine and other opiates. At present it is thought that the morphine-like effects are due to aromatic side chains on phenylanine and tyrosine which mimic a similar sturcture on morphine. Apparently, it does not make much difference whether the enkephalin contains methionine or leucine at the acid end of the peptide.

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