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  • 11.9: Nucleophilic Acyl Substitution Reactions in the Laboratory
    https://chem.libretexts.org/Courses/Oregon_Institute_of_Technology/OIT%3A_CHE_332_--_Organic_Chemistry_II_(Lund)/11%3A_Nucleophilic_Acyl_Substitution_Reactions/11.9%3A_Nucleophilic_Acyl_Substitution_Reactions_in_the_Laboratory
    All of the biological nucleophilic acyl substitution reactions we have seen so far have counterparts in laboratory organic synthesis. Mechanistically, one of the biggest differences between the biolog...All of the biological nucleophilic acyl substitution reactions we have seen so far have counterparts in laboratory organic synthesis. Mechanistically, one of the biggest differences between the biological and the lab versions is that the lab reactions usually are run with a strong acid or base as a catalyst, whereas biological reactions are of course taking place at physiological pH.
  • 11.9: Nucleophilic Acyl Substitution Reactions in the Laboratory
    https://chem.libretexts.org/Courses/Oregon_Institute_of_Technology/OIT%3A_CHE_333_-_Organic_Chemistry_III_(Lund)/New_Page/11%3A_Nucleophilic_Acyl_Substitution_Reactions/11.9%3A_Nucleophilic_Acyl_Substitution_Reactions_in_the_Laboratory
    All of the biological nucleophilic acyl substitution reactions we have seen so far have counterparts in laboratory organic synthesis. Mechanistically, one of the biggest differences between the biolog...All of the biological nucleophilic acyl substitution reactions we have seen so far have counterparts in laboratory organic synthesis. Mechanistically, one of the biggest differences between the biological and the lab versions is that the lab reactions usually are run with a strong acid or base as a catalyst, whereas biological reactions are of course taking place at physiological pH.