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- https://chem.libretexts.org/Courses/Smith_College/CHM_222_Chemistry_II%3A_Organic_Chemistry_(2025)/11%3A_Carboxylic_Acids_and_Nitriles/11.07%3A_Reactions_of_Carboxylic_Acids_-_An_OverviewFour general reaction categories are represented here: (1) As carboxylic acid deprotonates quite readily, it is quite easy to form a carboxylate salt or to substitute the hydroxyl hydrogen. (2) The ca...Four general reaction categories are represented here: (1) As carboxylic acid deprotonates quite readily, it is quite easy to form a carboxylate salt or to substitute the hydroxyl hydrogen. (2) The category of nucleophilic acyl substitution represents the substitution of the whole hydroxyl group, which we will see later in more detail leads to several carboxylic acid derivatives (e.g.
- https://chem.libretexts.org/Courses/Smith_College/Organic_Chemistry_(LibreTexts)/20%3A_Carboxylic_Acids_and_Nitriles/20.07%3A_Reactions_of_Carboxylic_Acids_-_An_OverviewFour general reaction categories are represented here: (1) As carboxylic acid deprotonates quite readily, it is quite easy to form a carboxylate salt or to substitute the hydroxyl hydrogen. (2) The ca...Four general reaction categories are represented here: (1) As carboxylic acid deprotonates quite readily, it is quite easy to form a carboxylate salt or to substitute the hydroxyl hydrogen. (2) The category of nucleophilic acyl substitution represents the substitution of the whole hydroxyl group, which we will see later in more detail leads to several carboxylic acid derivatives (e.g.
- https://chem.libretexts.org/Bookshelves/Organic_Chemistry/Organic_Chemistry_II_(Morsch_et_al.)/20%3A_Carboxylic_Acids_and_Nitriles/20.06%3A_Reactions_of_Carboxylic_Acids_-_An_OverviewFour general reaction categories are represented here: (1) As carboxylic acid deprotonates quite readily, it is quite easy to form a carboxylate salt or to substitute the hydroxyl hydrogen. (2) The ca...Four general reaction categories are represented here: (1) As carboxylic acid deprotonates quite readily, it is quite easy to form a carboxylate salt or to substitute the hydroxyl hydrogen. (2) The category of nucleophilic acyl substitution represents the substitution of the whole hydroxyl group, which we will see later in more detail leads to several carboxylic acid derivatives (e.g.
- https://chem.libretexts.org/Workbench/LCDS_Organic_Chemistry_OER_Textbook_-_Todd_Trout/20%3A_Carboxylic_Acids_and_Nitriles/20.07%3A_Reactions_of_Carboxylic_Acids_-_An_OverviewWe commented earlier in this chapter that carboxylic acids are similar in some respects to both alcohols and ketones. Figure 20.3 shows some of the general reactions of carboxylic acids. Reactions of ...We commented earlier in this chapter that carboxylic acids are similar in some respects to both alcohols and ketones. Figure 20.3 shows some of the general reactions of carboxylic acids. Reactions of carboxylic acids can be grouped into the four categories indicated in Figure 20.3. Of the four, we’ve already discussed the acidic behavior of carboxylic acids in Section 20.2 through Section 20.4, and we mentioned reduction by treatment with LiAlH 4 in Section 17.4.
- https://chem.libretexts.org/Courses/can/CHEM_232_-_Organic_Chemistry_II_(Puenzo)/06%3A_Carboxylic_Acids_and_Nitriles/6.06%3A_Reactions_of_Carboxylic_Acids_-_An_OverviewYou may wish to review the reduction of carbonyl compounds to form alcohols (OCHEM I) and the acidity of carboxylic acids, which is important to salt formation and substitution of the hydroxyl hydroge...You may wish to review the reduction of carbonyl compounds to form alcohols (OCHEM I) and the acidity of carboxylic acids, which is important to salt formation and substitution of the hydroxyl hydrogen. In the first step of the reduction mechanism, which is rate determining, the acidic hydrogens of three carboxylic acids along with the three hydrogens from BH 3 are rapidly removed to form hydrogen gas (H 2 ) and a triacyloxyborane complex.
- https://chem.libretexts.org/Courses/Martin_Luther_College/Organic_Chemistry_-_MLC/04%3A_Carbonyls/4.02%3A_Carboxylic_Acids/4.2.04%3A_Reactions_of_Carboxylic_Acids_-_An_OverviewFour general reaction categories are represented here: (1) As carboxylic acid deprotonates quite readily, it is quite easy to form a carboxylate salt or to substitute the hydroxyl hydrogen. (2) The ca...Four general reaction categories are represented here: (1) As carboxylic acid deprotonates quite readily, it is quite easy to form a carboxylate salt or to substitute the hydroxyl hydrogen. (2) The category of nucleophilic acyl substitution represents the substitution of the whole hydroxyl group, which we will see later in more detail leads to several carboxylic acid derivatives (e.g.
