In addition to proteins and nucleic acids, the majority of pharmaceutical agents contain amine functional groups, and many of the common coenzymes necessary for biological catalysis are amines. Trimet...In addition to proteins and nucleic acids, the majority of pharmaceutical agents contain amine functional groups, and many of the common coenzymes necessary for biological catalysis are amines. Trimethylamine, for instance, occurs in animal tissues and is partially responsible for the distinctive odor of fish; nicotine is found in tobacco; and cocaine is a stimulant found in the leaves of the South American coca bush.