Certain household chemicals, such as some brands of cleanser, can be very concentrated bases, which makes them among the most potentially hazardous substances found around the home; if spilled on the ...Certain household chemicals, such as some brands of cleanser, can be very concentrated bases, which makes them among the most potentially hazardous substances found around the home; if spilled on the skin, the strong caustic compound can immediately remove H+ ions from the flesh, resulting in chemical burns. Compare that to the fact that we occasionally purposefully ingest substances such as citrus fruits, vinegar, and wine-all of which contain acids.