When it comes to buffer solution one of the most common equation is the Henderson-Hasselbalch approximation. An important point that must be made about this equation is it's useful only if stoichiomet...When it comes to buffer solution one of the most common equation is the Henderson-Hasselbalch approximation. An important point that must be made about this equation is it's useful only if stoichiometric or initial concentration can be substituted into the equation for equilibrium concentrations.