Acetyl-CoA is one of the most “connected" metabolites in biochemistry, appearing in fatty acid oxidation/reduction, pyruvate oxidation, the citric acid cycle, amino acid anabolism/catabolism, ketone b...Acetyl-CoA is one of the most “connected" metabolites in biochemistry, appearing in fatty acid oxidation/reduction, pyruvate oxidation, the citric acid cycle, amino acid anabolism/catabolism, ketone body metabolism, steroid/bile acid synthesis, and (by extension from fatty acid metabolism) prostaglandin synthesis. Most of these pathways will be dealt with separately. Here we will cover the last three.