In the words of the author of the strategy, "although the particular synthetic plan followed for the construction of the tetracyclic system had no particular basis in biogenetic considerations, very r...In the words of the author of the strategy, "although the particular synthetic plan followed for the construction of the tetracyclic system had no particular basis in biogenetic considerations, very recent work has suggested a biogenetic pathway in which the crucial cyclization step is strikingly similar to the one we devised."