In isotope dilution, an external source of analyte is prepared in a radioactive form with a known activity. We add a known mass of the tracer to a portion of sample that contains an unknown mass of an...In isotope dilution, an external source of analyte is prepared in a radioactive form with a known activity. We add a known mass of the tracer to a portion of sample that contains an unknown mass of analyte. Analyzing for the total amount of analyte and amount of activity allows us to determine the amount of analyte in the original sample.
