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- https://chem.libretexts.org/Courses/University_of_Alberta_Augustana_Campus/AUCHE_252_-_Organic_Chemistry_II/05%3A_Aldehydes_and_Ketones/5.06%3A_Carbonyl_Condensations_-_The_Aldol_ReactionA useful carbon-carbon bond-forming reaction known as the Aldol Reaction is another example of electrophilic substitution at the alpha carbon in enolate anions. In the reaction’s product, the formed C...A useful carbon-carbon bond-forming reaction known as the Aldol Reaction is another example of electrophilic substitution at the alpha carbon in enolate anions. In the reaction’s product, the formed C-C bond links a carbon in the alpha position and a carbon in the beta position away from the carbonyl. The alpha carbon and the electrophilic carbon of the reactants should be identified in the aldol product to assess their possible chirality.
- https://chem.libretexts.org/Courses/Smith_College/CHM_223_Chemistry_III%3A_Organic_Chemistry_(2024)/07%3A_Carbonyl_Condensation_Reactions/7.02%3A_Carbonyl_Condensations_-_The_Aldol_ReactionThe fundamental transformation in the aldol reaction is a dimerization of an aldehyde (or ketone) to form a beta-hydroxy aldehyde (or ketone). In the reaction’s product, the formed C-C bond links a ca...The fundamental transformation in the aldol reaction is a dimerization of an aldehyde (or ketone) to form a beta-hydroxy aldehyde (or ketone). In the reaction’s product, the formed C-C bond links a carbon in the alpha position and a carbon in the beta position away from the carbonyl. The alpha carbon and the electrophilic carbon of the reactants should be identified in the aldol product to assess their possible chirality.
- https://chem.libretexts.org/Bookshelves/Organic_Chemistry/Organic_Chemistry_(Morsch_et_al.)/23%3A_Carbonyl_Condensation_Reactions/23.01%3A_Carbonyl_Condensations_-_The_Aldol_ReactionThe fundamental transformation in the aldol reaction is a dimerization of an aldehyde (or ketone) to form a beta-hydroxy aldehyde (or ketone). In the reaction’s product, the formed C-C bond links a ca...The fundamental transformation in the aldol reaction is a dimerization of an aldehyde (or ketone) to form a beta-hydroxy aldehyde (or ketone). In the reaction’s product, the formed C-C bond links a carbon in the alpha position and a carbon in the beta position away from the carbonyl. The alpha carbon and the electrophilic carbon of the reactants should be identified in the aldol product to assess their possible chirality.
- https://chem.libretexts.org/Bookshelves/Organic_Chemistry/Supplemental_Modules_(Organic_Chemistry)/Reactions/Reactivity_of_Alpha_Hydrogens/Aldol_ReactionA useful carbon-carbon bond-forming reaction known as the Aldol Reaction is yet another example of electrophilic substitution at the alpha carbon in enolate anions. The fundamental transformation in t...A useful carbon-carbon bond-forming reaction known as the Aldol Reaction is yet another example of electrophilic substitution at the alpha carbon in enolate anions. The fundamental transformation in this reaction is a dimerization of an aldehyde (or ketone) to a beta-hydroxy aldehyde (or ketone) by alpha C–H addition of one reactant molecule to the carbonyl group of a second reactant molecule.
- https://chem.libretexts.org/Courses/can/CHEM_232_-_Organic_Chemistry_II_(Puenzo)/09%3A_Carbonyl_Condensation_Reactions/9.02%3A_Carbonyl_Condensations_-_The_Aldol_ReactionThe fundamental transformation in the aldol reaction is a dimerization of an aldehyde (or ketone) to form a beta-hydroxy aldehyde (or ketone). In the reaction’s product, the formed C-C bond links a ca...The fundamental transformation in the aldol reaction is a dimerization of an aldehyde (or ketone) to form a beta-hydroxy aldehyde (or ketone). In the reaction’s product, the formed C-C bond links a carbon in the alpha position and a carbon in the beta position away from the carbonyl. The alpha carbon and the electrophilic carbon of the reactants should be identified in the aldol product to assess their possible chirality.
- https://chem.libretexts.org/Bookshelves/Organic_Chemistry/Organic_Chemistry_II_(Morsch_et_al.)/23%3A_Carbonyl_Condensation_Reactions/23.01%3A_Carbonyl_Condensations_-_The_Aldol_ReactionThe fundamental transformation in the aldol reaction is a dimerization of an aldehyde (or ketone) to form a beta-hydroxy aldehyde (or ketone). In the reaction’s product, the formed C-C bond links a ca...The fundamental transformation in the aldol reaction is a dimerization of an aldehyde (or ketone) to form a beta-hydroxy aldehyde (or ketone). In the reaction’s product, the formed C-C bond links a carbon in the alpha position and a carbon in the beta position away from the carbonyl. The alpha carbon and the electrophilic carbon of the reactants should be identified in the aldol product to assess their possible chirality.
- https://chem.libretexts.org/Courses/Smith_College/Organic_Chemistry_(LibreTexts)/23%3A_Carbonyl_Condensation_Reactions/23.02%3A_Carbonyl_Condensations_-_The_Aldol_ReactionThe fundamental transformation in the aldol reaction is a dimerization of an aldehyde (or ketone) to form a beta-hydroxy aldehyde (or ketone). In the reaction’s product, the formed C-C bond links a ca...The fundamental transformation in the aldol reaction is a dimerization of an aldehyde (or ketone) to form a beta-hydroxy aldehyde (or ketone). In the reaction’s product, the formed C-C bond links a carbon in the alpha position and a carbon in the beta position away from the carbonyl. The alpha carbon and the electrophilic carbon of the reactants should be identified in the aldol product to assess their possible chirality.
- https://chem.libretexts.org/Bookshelves/Organic_Chemistry/Organic_Chemistry_(OpenStax)/23%3A_Carbonyl_Condensation_Reactions/23.01%3A_Carbonyl_Condensations_-_The_Aldol_ReactionThe Aldol reaction is a carbonyl condensation reaction that forms carbon-carbon bonds by combining an enolate ion with an aldehyde or ketone, producing β-hydroxy aldehydes or ketones. This reaction is...The Aldol reaction is a carbonyl condensation reaction that forms carbon-carbon bonds by combining an enolate ion with an aldehyde or ketone, producing β-hydroxy aldehydes or ketones. This reaction is key in organic synthesis for creating more complex molecules. The product can further undergo dehydration to form α,β-unsaturated carbonyl compounds, which are important intermediates in both biological systems and synthetic chemistry.
- https://chem.libretexts.org/Workbench/LCDS_Organic_Chemistry_OER_Textbook_-_Todd_Trout/23%3A_Carbonyl_Condensation_Reactions/23.02%3A_Carbonyl_Condensations_-_The_Aldol_ReactionFor example, treatment of acetaldehyde with a base such as sodium ethoxide or sodium hydroxide in a protic solvent leads to rapid and reversible formation of 3-hydroxybutanal, known commonly as aldol ...For example, treatment of acetaldehyde with a base such as sodium ethoxide or sodium hydroxide in a protic solvent leads to rapid and reversible formation of 3-hydroxybutanal, known commonly as aldol (aldehyde + alcohol), hence the general name of the reaction. An aldol reaction combines two molecules of reactant by forming a bond between the α carbon of one partner and the carbonyl carbon of the second partner.
